Summary
BLG-Cre transgenic line 74 shows specific expression in the mammary gland, predominantly
during lactation. Cre mediated recombination takes place in 80-90% of lactating mammary
tissue.
Citation
Selbert S, Bentley DB, Melton DW, Rannie D, Lourenco P, Watson CJ and Clarke AR (1998)
Efficient BLG-Cre mediated gene deletion in the mammary gland
Transgenic Research 7(5), 387-396
Contributers
The fusion construct was built by Stefan Selbert, the promotor was obtained from John Clark and transgenic mice have been analyzed together with Dominic Rannie and Paula Lourenco.
For further information please contact: Stefan Selbert (stefan@srv4.med.ed.ac.uk), Christine Watson (cwatson@ed.ac.uk) or Alan Clarke (aclarke@ed.ac.uk)
Click here for more information about Cre mediated gene deletion in the mammary gland using WAP-Cre and MMTV-Cre transgenic mice. A short review about the Cre-lox recombination system is also available.
contributed January, 1998