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The establishment of gene knock-out mice has identified genes which play critical roles in mammary gland development, function and tumorigenesis. Information on such mice is provided on this page.
2.1.Hormones and Receptors
2.2. Transcription Factors
2.3. Cell Cycle Proteins
2.4. Phosphatases
2.5. Cell Adhesion Molecules
2.6. Milk Proteins
2.1. Hormones and Receptors
2.1.1 estrogen receptor
alpha
2.1.2 estrogen receptor beta
2.1.3 Progesterone Receptor
2.1.4 Prolactin
2.1.5 Prolactin Receptor
2.1.6 Oxytocin
2.1.7 Oxytocin Receptor
2.1.8 CSF-1
2.1.9 activin / inhibin
2.1.10 Parathyroid hormone related peptide
2.1.11 Parathyroid hormone related peptide receptor
2.1.12 SRC-1
2.1.13 epidermal growth factor receptor
2.1.14 Galanin
2.1.15 c-cbl
2.1.16 Relaxin-deficient Mice
2.1.17 Aromatase-deficient Mice
2.2. Transcription Factors
2.2.1 Stat5a
2.2.2 Stat5b
2.2.3 Stat5a/Stat5b
2.2.4 C/EBPbeta
2.2.5 fosB
2.2.6 winged helix gene Mf3
2.2.7 mox-1
2.2.8 A-myb
2.2.9 Hoxa9, Hoxb9, Hoxd9
2.3. Cell Cycle Proteins
2.3.1 p53 Inactivation
through T-antigen
2.3.2 wnt1 in the Absence of p53
2.3.3 pRb
2.3.4 cyclinD1
2.4. Phosphatases
2.4.1 LAR