Summary
KIM-2 conditionally immortal mammary epithelial cells differentiated in the presence of insulin, dexamethasone and prolactin. The pulsating dome-like structures are indicative of tight junctions and transepithelial fluid transport. Shots every 10 minutes.
Differentiated KIM-2 cells induced to undergo apoptosis by the removal of lactogenic hormones and reduction of serum to 3%. Dying cells can be observed and this appears to result in destroying the integrity of the domes which eventually stop pulsating and collapse completely.
Keywords
Contributed By
Christine Watson and Rachel Chapman
University of Edinburgh
Edinburgh, Scotland
Phone: 44-131-651 1081
Fax: 44-131-651 1072
E-mail: (cwatson@srv4.med.ed.ac.uk)
contributed: June, 1997 |
