INTRODUCTION
for additional information on this model see WAP-TAg transgenic mice
References
Li, M., Liu, X., Robinson, G., Bar-Paled, U., Wagner, K-U, Young, W.S, Hennighausen, L.
and Furth, P.A. (1997) Mammary derived signals activate programmed cell during the
involuting mammary gland. Proc. Natl. Acad. Sci. U.S.A., 94, 3425-3430. (Medline
Abstract).
(PDF reprint)
Heermeier, K. Benedikt, M., Li. M., Furth, P.A., Nunez, G. and Hennighausen, L. (1996) Induction of the apoptosis proteins bax and bcl-xS coincides with the onset of programmed cell death in involuting mammary epithelial cells. Mech. of Development, 56, 197-207.
Li, M., Hu, J., Heermeier, K., Hennighausen, L. and Furth, P.A. (1996a) Expression of a viral oncoprotein during mammary gland development altyers cel fate and function: induction of p53 independent apoptosis is followed by impaired milk production in surviving cells. Cell Growth & Differentiation 7, 3-11. Medline Abstract
Li, M., Hu, J., Heermeier, K., Hennighausen, L. and Furth, P.A. (1996b) Apoptosis and remodeling of mammary gland tissue during involution proceeds through p53 independent pathways. Cell Growth & Differentiation 7, 13-20 (Medline Abstract).
Tzeng, Y.-J., Guhl, M., Graessmann, M. and Graessmann, A. (1993) Breast cancer formation in transgenic animals induced by the whey acidic protein SV40T antigen (WAP-SV-T) hybrid gene. Oncogene 8, 1965-1971.
Submitted by:
Priscilla A Furth, MD
Institute of Human Virology and the Departments of Medicine and Physiology
University of Maryland Medical School
Baltimore, MD 21201
Telephone: (401) 706-4606
Fax: (410) 706-1992
email: furth@umbi.umd.edu
and
Minglin Li, PhD
Institute of Human Virology and the Department of Medicine
University of Maryland Medical School
Baltimore, MD 21201
Telephone: (401) 706-4606
Fax: (410) 706-1992
Last Updated: December 1998